The heat shock protein 90 (Hsp90) is a molecular chaperone that activates and maintains the biological functioning of several client proteins, many of which are associated with oncogenic signaling pathways.

Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 cell lines in a dose-dependent manner and induce the significant increase of the G0/G1 cell population.

MDH1-IN-2 (7c) is a potent MDH1 inhibitor with an IC50 of 2.27 μM for MDH1 and 27.47 μM for MDH2. MDH1-IN-2 has potential anticancer activity and can be used in the study of diseases related to the immune system.