3-Hexenedioic acid is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorders The urinary excretion of 3-Hexenedioic acid is increased in conditions of augmented mobilization of fatty acids or inhibited fatty acid oxidation.

Alclometasone dipropionate （Sch 22219） is a synthetic glucocorticoid, a steroidal compound with antiproliferative, anti-inflammatory, anti-allergic, antipruritic, and vasoconstrictive properties, which is used in the study of skin inflammation.

SMS2-IN-1 is a highly selective inhibitor of sphingomyelin synthase 2 (SMS2)(IC50 of 6.5 nM).