RES-701-1( ——— )

Catalog No. M42049 CAS No. 151308-34-8

RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ETB receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

RES-701-1
Note

Research use only, not for human use.
Brief Description

RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ETB receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM.
Description

RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ETB receptor.
In Vitro

———
In Vivo

———
Synonyms

———
Pathway

Others
Target

Other Targets
Recptor

ETB: 10 nM (IC50)]
Research Area

———
Indication

———

Chemical Information

CAS Number

151308-34-8
Formula Weight

2061.22
Molecular Formula

C103H117N23O24
Purity

>98% (HPLC)
Solubility

———
SMILES

———
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Tanaka T, et al. RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin. Mol Pharmacol. 1994 Apr;45(4):724-30.?

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