Flurocitabine HCl is a fluorinated anhydride analog of cytarabine, which is partially hydrolyzed in vivo to two active antitumor substances (arabinosyl-fluorouracil (ara-FC) and arabinosyl-fluorouracil (ara-FU)).

KHK-IN-1 is a reversible and ATP-competitive inhibitor of ketohexokinase (KHK) with IC50 of 12 nM. In the ATP-binding region of KHK, KHK-IN-1 interacts with Asp-27B.

Cotadutide acetate (MEDI0382 acetate) is a potent peptide?dual?agonist?of glucagon-like?peptide-1?(GLP-1) and?glucagon?receptor with EC50 values of 6.9 pM and 10.2 pM, respectively.