CKS-17
CAS No. 99273-04-8
CKS-17( ——— )
Catalog No. M41863 CAS No. 99273-04-8
CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 50MG | Get Quote | Get Quote |
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| 100MG | Get Quote | Get Quote |
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Biological Information
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Product NameCKS-17
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NoteResearch use only, not for human use.
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Brief DescriptionCKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions.
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DescriptionCKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions.
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In VitroCKS-17 (THP-1 cells) induces increased intracellular cAMP via activation of adenylate cyclase.CKS-17 (15 μM; EL4 cells) inhibits interleukin-2 production by tumor cell products.
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In VivoCKS-17 (10 μM; i.d.; B6AF1 mice and C57BL/6J mice) inhibits delayed-type hypersensitivity (DTH) reactions to sheep erythrocytes in the feet of mice.Animal Model:B6AF1 mice and C57BL/6J mice with DTH models Dosage:10 μM Administration: Intradermal injection, into the right hind footpad Result:Had a transient depressive effect on DTH reaction.
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number99273-04-8
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Formula Weight1942.31
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Molecular FormulaC87H148N26O24
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Haraguchi S, et, al. Induction of intracellular cAMP by a synthetic retroviral envelope peptide: a possible mechanism of immunopathogenesis in retroviral infections. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5568-71.?
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