Bintrafusp alfa (M7824) is a bifunctional fusion protein consisting of the extracellular structural domain of TGF-βRII (a TGF-β “trap”) fused to a monoclonal antibody against human immunoglobulin G1 fused to programmed death ligand 1 (PD-L1).

Lefamulin is a semi-synthetic compound that inhibits the synthesis of bacterial protein, which is required for bacteria to grow.

Tigloylgomisin P shows moderate to marginal cytotoxicity against A549, PC-3, KB and KBvin human cancer cell lines.