Pancreatic Polypeptide, human b( ——— )

Catalog No. M41488 CAS No. 59763-91-6

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Product Name

Pancreatic Polypeptide, human b
Note

Research use only, not for human use.
Brief Description

Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion.
Description

Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion.
In Vitro

Pancreatic polypeptid (PP) (0.1μM, 48 h) causes a significant reduction in growth inhibitory hormone secretion in mHippo E18 cells.
In Vivo

Pancreatic polypeptid (PP)(1μM, Hippocampal injection, 0.2μL/min followed by 3min) stimulates the expression of the neuronal activation marker c-Fos in growth inhibitor-containing cells in the male B6C3F1/J mice brain, indicating that it activates growth inhibitor-containing cells in the mouse hippocampus.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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1. Wook Kim, et al. Pancreatic polypeptide inhibits somatostatin secretion. FEBS Lett. 2014 Aug 25;588(17):3233-9.?

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