Adipokinetic Hormone II Locusta Migratoria
CAS No. 98968-94-6
Adipokinetic Hormone II Locusta Migratoria( ——— )
Catalog No. M40641 CAS No. 98968-94-6
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
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Biological Information
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Product NameAdipokinetic Hormone II Locusta Migratoria
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NoteResearch use only, not for human use.
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Brief DescriptionAdipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs).
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DescriptionAdipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro.
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In VitroAdipokinetic hormone II (Locusta migratoria) (radiolabeled; 1 pmol in 10 μL of 10% methanol; 30 min on ice, and repeated for 2 h at 30 ℃) shows no association with one of the larger protein components, indicating a lack of separate transporting or carrier protein in the hemolymph.Adipokinetic hormones (AKHs) are known to be involved in insect immunity and shows the mechanism of metabolic stimulation, leading a significant increase in carbon dioxide production,and efficacy increase of toxins produced by I. fumosorosea in the cockroach's body.Adipokinetic hormone II is more effective than hormone I in bringing about an accumulation of cAMP in the fat body.
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In VivoAdipokinetic hormone II (Locusta migratoria) (1 pmol in 10 μL of 10% methanol; injection) plays its own biol. role in the overall syndrome of insect flight, with different half-lives of 40 min and 37 min during rest and flight, respectively.
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number98968-94-6
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Formula Weight904.02
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Molecular FormulaC43H57N11O11
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Oudejans RC, et al. Locust adipokinetic hormones: carrier-independent transport and differential inactivation at physiological concentrations during rest and flight. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8654-9.?
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