Neuropeptide Y (2-36) (porcine)( ——— )

Catalog No. M40286 CAS No. 102961-52-4

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Product Name

Neuropeptide Y (2-36) (porcine)
Note

Research use only, not for human use.
Brief Description

Neuropeptide Y (2-36) (porcine) is a porcine-derived neuropeptide with 97.14% homology to rat/human origin. Neuropeptide Y (2-36) (porcine) is also a rat neuropeptide receptor agonist, with EC50 values of 1.2, 1.6 and 3.4 nM for receptor of Y5, Y2 and Y1 respectively. Neuropeptide Y (2-36) (porcine) can be used in studies related to obesity and eating disorders.
Description

Neuropeptide Y (2-36) (porcine) is a porcine-derived neuropeptide with 97.14% homology to rat/human origin. Neuropeptide Y (2-36) (porcine) is also a rat neuropeptide receptor agonist, with EC50 values of 1.2, 1.6 and 3.4 nM for receptor of Y5, Y2 and Y1 respectively. Neuropeptide Y (2-36) (porcine) can be used in studies related to obesity and eating disorders.
In Vitro

The following information is for reference:Neuropeptide Y (2-36) (porcine): PSKPDNPGEDAPAEDLARYYSALRHYINLITRQRY-NH2；Neuropeptide Y (2-36) (human, rat): PSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2 (97.14% homology to porcine).
In Vivo

Neuropeptide Y (2-36) (porcine) (1.23 μg/rat; i.c.v.; single) induces food intake in rats.Animal Model:Male Sprague-Dawley rats (180-220 g).Dosage:1.23 μg/rat (300 pmol/rat) Administration:Intracerebroventricular injection; single Result:Increased food intake to 5.0 g 4 hours later.
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Indication

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1. Gerald C, et al. A receptor subtype involved in neuropeptide-Y-induced food intake. Nature. 1996 Jul 11;382(6587):168-71. ?

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