β-Endorphin (human)

Research use only, not for human use.

β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus, is an agonist of opioid receptor, with preferred affinity for μ-opioid receptor and δ-opioid receptor; β-Endorphin, human exhibits antinociception activity.

β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus,and is an agonist of opioid receptor.

β-Endorphin, human is an agonist of opioid receptor, with preferred affinity for μ-opioid receptor and δ-opioid receptor. β-Endorphin exhibits anti-nociception activity by stimulating ε-opioid receptor, rather than μ-, δ-, and κ-opioid receptor. β-Endorphin has anti-nociception activity. Firstly, β-Endorphin combines together with the opioid receptors in hyperalgesia. Further, β-Endorphin suppresses the release of substance P at the level of spinal cord and blocks the conduction of pain on the primary sensory neurons. Moreover, β-Endorphin activates the endogenous analgesia system located in the CNS. In addition, β-Endorphin inhibits the conduction of pain and agitation of nociceptors to exert an analgesic effect.

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Endocrinology/Hormones

Opioid Receptor

Opioid receptor

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61214-51-5

3464.98

C158H251N39O46S

>98% (HPLC)

DMSO : 100 mg/mL (28.86 mM; ultraphonic; ) H2O : ≥ 50 mg/mL (14.43 mM)

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(-20℃)

With Ice Pack

≥ 2 years