H-Tyr-Ile-Gly-Ser-Arg-OH( ——— )

Catalog No. M39996 CAS No. 110590-64-2

YIGSR is a peptide that can inhibit the tumour growth and metastasis of leukaemic cells. YIGSR blocks the cellular binding to laminin I via a 67-kDa laminin-binding protein, and inhibits shear-induced increase in eNOS expression of laminin cells.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

H-Tyr-Ile-Gly-Ser-Arg-OH
Note

Research use only, not for human use.
Brief Description

YIGSR is a peptide that can inhibit the tumour growth and metastasis of leukaemic cells. YIGSR blocks the cellular binding to laminin I via a 67-kDa laminin-binding protein, and inhibits shear-induced increase in eNOS expression of laminin cells.
Description

YIGSR is a peptide that can inhibit the tumour growth and metastasis of leukaemic cells.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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Chemical Information

CAS Number

110590-64-2
Formula Weight

594.7
Molecular Formula

C26H42N8O8
Purity

>98% (HPLC)
Solubility

———
SMILES

———
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. N Yoshida, et al. The laminin-derived peptide YIGSR (Tyr–Ile–Gly–Ser–Arg) inhibits human pre-B leukaemic cell growth and dissemination to organs in SCID mice. Br J Cancer. 1999 Aug; 80(12): 1898–1904.

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