Cart
sales@molnova.com
16-dimethyl PGE2
CAS No. 39746-25-3
16-dimethyl PGE2( ——— )
Catalog No. M39447 CAS No. 39746-25-3
16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 305 | In Stock |
|
| 25MG | Get Quote | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name16-dimethyl PGE2
-
NoteResearch use only, not for human use.
-
Brief Description16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.
-
Description16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway.
-
In Vitro———
-
In VivoAnimal Model:Tpl2IMF-KO mice Dosage:10 μg/kg Administration:IP; every 12 hours; for 8 days Result:Rescued the exacerbated DSS colitis phenotype and restores epithelial proliferation and structure.
-
Synonyms———
-
PathwayGPCR/G Protein
-
TargetProstaglandin Receptor
-
RecptorEP2
-
Research Area———
-
Indication———
Chemical Information
-
CAS Number39746-25-3
-
Formula Weight380.52
-
Molecular FormulaC22H36O5
-
Purity>98% (HPLC)
-
SolubilityDMSO : 100 mg/mL (262.80 mM; ultraphonic; )
-
SMILES———
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hagedorn EJ, et al. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. xp Cell Res. 2014 Dec 10;329(2):220-6.?
molnova catalog
related products
-
Treprostinil diethan...
Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1, and IP, with values of 3.6, 4.4, and 32.1 nM for EP2, DP1, and IP, respectively, and 212, 826, 2505, and 4680 nM for EP1, EP4, EP3, and FPKi, respectively.
-
Aligeron
Aligeron, a non-selective prostaglandin (PG) antagonist, inhibits PGF2α- and PGE2-induced blood pressure decreases in cats and can prevent PGF2α-induced diarrhea in mice and PGE2-induced paw edema in rats.
-
GW 627368X
GW627368(GW627368X) is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor(Ki= 100 nM) with additional human TP receptor affinity(Ki= 150 nM).
