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16-dimethyl PGE2

CAS No. 39746-25-3

16-dimethyl PGE2( ——— )

Catalog No. M39447 CAS No. 39746-25-3

16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

16-dimethyl PGE2
Note

Research use only, not for human use.
Brief Description

16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.
Description

16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway.
In Vitro

———
In Vivo

Animal Model:Tpl2IMF-KO mice Dosage:10 μg/kg Administration:IP; every 12 hours; for 8 days Result:Rescued the exacerbated DSS colitis phenotype and restores epithelial proliferation and structure.
Synonyms

———
Pathway

GPCR/G Protein
Target

Prostaglandin Receptor
Recptor

EP2
Research Area

———
Indication

———

Chemical Information

CAS Number

39746-25-3
Formula Weight

380.52
Molecular Formula

C22H36O5
Purity

>98% (HPLC)
Solubility

DMSO : 100 mg/mL (262.80 mM; ultraphonic; )
SMILES

———
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hagedorn EJ, et al. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. xp Cell Res. 2014 Dec 10;329(2):220-6.?

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