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Tanshinone IIB

CAS No. 17397-93-2

Tanshinone IIB( ——— )

Catalog No. M39087 CAS No. 17397-93-2

Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tanshinone IIB
  • Note
    Research use only, not for human use.
  • Brief Description
    Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis.
  • Description
    Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner.
  • In Vitro
    ———
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    P-gp;Bcl-2;Caspase
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    17397-93-2
  • Formula Weight
    310.349
  • Molecular Formula
    C19H18O4
  • Purity
    >98% (HPLC)
  • Solubility
    Methanol : 0.5 mg/mL (1.61 mM; ultraphonic)
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Xue-Qing Yu, et al. Tanshinone IIB, a primary active constituent from Salvia miltiorrhiza, exerts neuroprotective effect via inhibition of neuronal apoptosis in vitro. Phytother Res. 2008 Jun;22(6):846-50.?
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