Verbascose

CAS No. 546-62-3

Verbascose( ——— )

Catalog No. M38976 CAS No. 546-62-3

Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Verbascose
  • Note
    Research use only, not for human use.
  • Brief Description
    Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent.
  • Description
    Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent.
  • In Vitro
    Verbascose (25, 50, 100, 200, 400 μg/mL; 12, 24, 36, 48 hours) significantly increases the viability of RAW264.7 cells. Verbascose has notable activity of promoting peritoneal macrophages to devour neutral red in a dose-dependent manner and exhibits its maximum activity of cell phagocytosis at a concentration of 200 μg/mL. Verbascose induces significant increases of NO production. Verbascose can enhance the ability of devouring neutral red of peritoneal macrophages and promote the release of nitric oxide and immune reactive molecules such as interleukin (IL)-6, IL-1β, interferon (IFN)-α, and IFN-γ.
  • In Vivo
    Verbascose (30, 90, 120 mg/kg/day; sc; for 8 days) at a medium dose of 90 mg/kg body weight can significantly increase the index of spleen, activity of lysozyme in spleen and serum, hemolysin level in serum, and swelling rate of earlap in the delayed type of hypersensitivity (DTH) of immunosuppressed female Kunming mice.
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    546-62-3
  • Formula Weight
    828.73
  • Molecular Formula
    C30H52O26
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : 250 mg/mL (301.67 mM; ultraphonic)
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhuqing Dai, et al. Immunomodulatory activity in vitro and in vivo of verbascose from mung beans (Phaseolus aureus). J Agric Food Chem. 2014 Nov 5;62(44):10727-35.?
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