Verbascose

Research use only, not for human use.

Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent.

Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent.

Verbascose (25, 50, 100, 200, 400 μg/mL; 12, 24, 36, 48 hours) significantly increases the viability of RAW264.7 cells. Verbascose has notable activity of promoting peritoneal macrophages to devour neutral red in a dose-dependent manner and exhibits its maximum activity of cell phagocytosis at a concentration of 200 μg/mL. Verbascose induces significant increases of NO production. Verbascose can enhance the ability of devouring neutral red of peritoneal macrophages and promote the release of nitric oxide and immune reactive molecules such as interleukin (IL)-6, IL-1β, interferon (IFN)-α, and IFN-γ.

Verbascose (30, 90, 120 mg/kg/day; sc; for 8 days) at a medium dose of 90 mg/kg body weight can significantly increase the index of spleen, activity of lysozyme in spleen and serum, hemolysin level in serum, and swelling rate of earlap in the delayed type of hypersensitivity (DTH) of immunosuppressed female Kunming mice.

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Others

Other Targets

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546-62-3

828.73

C30H52O26

>98% (HPLC)

H2O : 250 mg/mL (301.67 mM; ultraphonic)

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(-20℃)

With Ice Pack

≥ 2 years