Methylsuccinic acid is a normal metabolite found in human fluids. Increased urinary levels of Methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy a rare metabolic disorder with an autosomal recessive mode of inheritance that is clinically characterized by neuromotor delay hyperlactic acidemia recurrent petechiae orthostatic acrocyanosis and chronic diarrhea.

CYM50260 is an exquisitely agonist of sphingosine-1-phosphate 4 receptor (S1P4-R) (EC50: 45 nM).

Secretin (28-54), human, which acts on human secretin receptors, is a 27-amino acid residue C-terminally amidated peptide, .