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Laurotetanine
CAS No. 128-76-7
Laurotetanine( ——— )
Catalog No. M38575 CAS No. 128-76-7
Laurotetanine ((+)-Laurotetanine) is an potent and orally active isoquinoline alkaloid and could be extracted from the roots of Litsea cubeba (Lour.) Pers. Laurotetanine exerts an anti-asthmatic effect by inhibition of IgE, histamine, and inflammatory reactions via down-regulating MUC5AC and NF-κB signaling pathways.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | Get Quote | Get Quote |
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| 50MG | Get Quote | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameLaurotetanine
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NoteResearch use only, not for human use.
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Brief DescriptionLaurotetanine ((+)-Laurotetanine) is an potent and orally active isoquinoline alkaloid and could be extracted from the roots of Litsea cubeba (Lour.) Pers. Laurotetanine exerts an anti-asthmatic effect by inhibition of IgE, histamine, and inflammatory reactions via down-regulating MUC5AC and NF-κB signaling pathways.
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DescriptionLaurotetanine is a bioactive chemical from Tetranthera & Lindera benzoin L. from family Lauraceae.
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In Vitro———
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In VivoAnimal Model:Sprague Dawley (SD) rats (180-220g) Dosage:20, 40, and 60 mg/kg Administration:Oral administration; daily, for 21 days Result:Reduced inflammatory cells, including eosinophils, neutrophils, lymphocytes, and macrophages.Decreased inflammatory cytokines viz IL-4, IL-6, IL-13 and increased IFN-γ.Reduced serum IgE and histamine.Decreased MUC5AC expression and increased NF-κB and IκB expression in lung tissues.
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number128-76-7
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Formula Weight327.37
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Molecular FormulaC19H21NO4
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xin XX, et, al. Anti-asthmatic effect of laurotetanine extracted from Litsea cubeba (Lour.) Pers. root on ovalbumin-induced allergic asthma rats, and elucidation of its mechanism of action. TROP J PHARM RES. 2019:18(6).
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