High affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Exhibits no significant effect on ACE enzymatic activity up to 500 nM concentration. Potentiates NMDA + D-serine-induced dopamine release from striatal slices in vitro and the striatum in vivo.

Glycyrrhizin-6'-methylester is a natural product that can be isolated from licorice (Glycyrrhiza glabra).

Kanshone A shows cytotoxic activity against P-388 cells.