Dimethylamine (DMA) is abundantly present in human urine. Main sources of urinary DMA have been reported to include trimethylamine N-oxide a common food component and asymmetric dimethylarginine (ADMA) an endogenous inhibitor of nitric oxide (NO) synthesis.

BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission and protected the cells from cell death.

KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.KIRA6 (10-1000 nM, 72 hours) strongly compromises the viability of the KIT-dependent cell line HMC-1.1 at the low nM concentration, in a manner that coincided with KIT blockade.