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L-Stepholidine
CAS No. 16562-13-3
L-Stepholidine( ——— )
Catalog No. M38112 CAS No. 16562-13-3
L-Stepholidine (Stepholidine) exhibits mixed dopamine D1 receptor agonist and D2 antagonist properties. L-Stepholidine has neuroprotective effect and inhibits Heroin-induced reinstatement. L-Stepholidine is a potential medication for the research of opiate addiction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameL-Stepholidine
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NoteResearch use only, not for human use.
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Brief DescriptionL-Stepholidine (Stepholidine) exhibits mixed dopamine D1 receptor agonist and D2 antagonist properties. L-Stepholidine has neuroprotective effect and inhibits Heroin-induced reinstatement. L-Stepholidine is a potential medication for the research of opiate addiction.
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DescriptionL-Stepholidine, which has dual actions on dopamine D1 and D2 receptors, attenuates heroin self-administration and cue-induced reinstatement.
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In Vitro———
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In Vivo———
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Synonyms———
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor;Dopamine Receptor
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Research Area———
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Indication———
Chemical Information
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CAS Number16562-13-3
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Formula Weight327.37
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Molecular FormulaC19H21NO4
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL (305.46 mM; (<60°C)）
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist.
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Hyperforin
Hyperforin is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels and triggers adipose tissue thermogenesis via the Dlat-AMPK signaling axis to suppress obesity. Hyperforin also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin modulates γδ T cells to secret IL-17α, improves Imiquimod -induced psoriasis-like mice model.
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Facinicline hydrochl...
Facinicline hydrochloride is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).
