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Anhydronotoptol

CAS No. 88206-51-3

Anhydronotoptol( —— )

Catalog No. M37804 CAS No. 88206-51-3

Anhydronotoptol (4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one), a natural compound extracted from the umbelliferae plant Qiangwu, is a potent inhibitor of nitric oxide production, inhibiting LPS-induced NO production in RAW 264.7 cells with an IC50 value of 36.6 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Anhydronotoptol
  • Note
    Research use only, not for human use.
  • Brief Description
    Anhydronotoptol (4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one), a natural compound extracted from the umbelliferae plant Qiangwu, is a potent inhibitor of nitric oxide production, inhibiting LPS-induced NO production in RAW 264.7 cells with an IC50 value of 36.6 μM.
  • Description
    Anhydronotoptol is a potent nitric oxide inhibitory coumarin. Anhydronotoptol inhibitsNO production in RAW 264.7 cells induced by LPS with an IC50 value of 36.6 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NO Synthase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    88206-51-3
  • Formula Weight
    336.38
  • Molecular Formula
    C21H20O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(C/C=C(/C/C=C/C(C)=C)\C)C=1C2=C(C=C3C1C=CO3)OC(=O)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Xikang Zheng, et al. Nitric oxide inhibitory coumarins from the roots and rhizomes of Notopterygium incisum.Fitoterapia. 2018 Nov;131:65-72.?
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