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Anhydronotoptol

CAS No. 88206-51-3

Anhydronotoptol( —— )

Catalog No. M37804 CAS No. 88206-51-3

Anhydronotoptol (4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one), a natural compound extracted from the umbelliferae plant Qiangwu, is a potent inhibitor of nitric oxide production, inhibiting LPS-induced NO production in RAW 264.7 cells with an IC50 value of 36.6 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Anhydronotoptol
Note

Research use only, not for human use.
Brief Description

Anhydronotoptol (4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one), a natural compound extracted from the umbelliferae plant Qiangwu, is a potent inhibitor of nitric oxide production, inhibiting LPS-induced NO production in RAW 264.7 cells with an IC50 value of 36.6 μM.
Description

Anhydronotoptol is a potent nitric oxide inhibitory coumarin. Anhydronotoptol inhibitsNO production in RAW 264.7 cells induced by LPS with an IC50 value of 36.6 μM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Immunology/Inflammation
Target

NOS
Recptor

NO Synthase
Research Area

——
Indication

——

Chemical Information

CAS Number

88206-51-3
Formula Weight

336.38
Molecular Formula

C21H20O4
Purity

>98% (HPLC)
Solubility

——
SMILES

O(C/C=C(/C/C=C/C(C)=C)\C)C=1C2=C(C=C3C1C=CO3)OC(=O)C=C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Xikang Zheng, et al. Nitric oxide inhibitory coumarins from the roots and rhizomes of Notopterygium incisum.Fitoterapia. 2018 Nov;131:65-72.?

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