Dehydroabietinol( —— )

Catalog No. M37767 CAS No. 3772-55-2

Dehydroabietinol (Pomiferin A) inhibits growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Dehydroabietinol
Note

Research use only, not for human use.
Brief Description

Dehydroabietinol (Pomiferin A) inhibits growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM).
Description

Dehydroabietinol is an abietane diterpenoid. Dehydroabietinol has kinase inhibition activity for spleen tyrosine kinase (SYK) with an IC50 value of 46.4 μM. Dehydroabietinol can be used for the research of immune-mediated disease.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Microbiology/Virology
Target

Antifection
Recptor

Antifection
Research Area

——
Indication

——

Chemical Information

CAS Number

3772-55-2
Formula Weight

286.45
Molecular Formula

C20H30O
Purity

>98% (HPLC)
Solubility

——
SMILES

C[C@@]12C=3C(CC[C@]1([C@@](CO)(C)CCC2)[H])=CC(C(C)C)=CC3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jun-Bo Gao, et al. Isolation, Characterization, and Structure-Activity Relationship Analysis of Abietane Diterpenoids from Callicarpa bodinieri as Spleen Tyrosine Kinase Inhibitors. J Nat Prod. 2018 Apr 27;81(4):998-1006.?

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