3,7,4-Trihydroxyflavone
CAS No. 2034-65-3
3,7,4-Trihydroxyflavone( —— )
Catalog No. M37743 CAS No. 2034-65-3
3,7,4'-Trihydroxyflavone(5-Deoxykampferol) is a DNA-breaking flavonoid isolated from rosewood heartwood.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 233 | In Stock |
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| 5MG | 148 | In Stock |
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| 10MG | 217 | In Stock |
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| 25MG | 440 | In Stock |
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| 50MG | 619 | In Stock |
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| 100MG | 863 | In Stock |
|
| 200MG | 1163 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name3,7,4-Trihydroxyflavone
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NoteResearch use only, not for human use.
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Brief Description3,7,4'-Trihydroxyflavone(5-Deoxykampferol) is a DNA-breaking flavonoid isolated from rosewood heartwood.
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Description3,7,4'-Trihydroxyflavone, isolated from Rhus javanica var. roxburghiana, is a flavonoid with DNA strand-scission activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA
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Research Area——
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Indication——
Chemical Information
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CAS Number2034-65-3
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Formula Weight270.24
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Molecular FormulaC15H10O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (370.04 mM; Ultrasonic )
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SMILESOc1ccc(cc1)-c1oc2cc(O)ccc2c(=O)c1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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HALOFUGINONE LACTATE
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM.?Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activityhalofuginone (HF), a widely studied derivative of febrifugine, inhibits the development of T(H)17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway.?HF binds glutamyl-prolyl-tRNA synthetase (EPRS), inhibiting prolyl-tRNA synthetase activity;?this inhibition is reversed by the addition of exogenous proline or EPRS.
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RU320521
RU.521 (RU320521) is a potent?dsDNA?inhibitor (IC50 : 700?nM) inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
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L82
L82 is a DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM) that is selective and non-competitive.L82 expresses anti-proliferative activity against breast cancer cells.
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