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PKCiota-IN-2

CAS No. 2230055-52-2

PKCiota-IN-2( —— )

Catalog No. M37688 CAS No. 2230055-52-2

PKCiota-IN-2 (PKCiota-IN-49) is a selective and potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	279	In Stock
2MG	166	In Stock
5MG	256	In Stock
10MG	375	In Stock
25MG	562	In Stock
50MG	776	In Stock
100MG	1042	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

PKCiota-IN-2
Note

Research use only, not for human use.
Brief Description

PKCiota-IN-2 (PKCiota-IN-49) is a selective and potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively
Description

PKCiota-IN-2 is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

PKC
Recptor

PKC
Research Area

——
Indication

——

Chemical Information

CAS Number

2230055-52-2
Formula Weight

395.46
Molecular Formula

C24H21N5O
Purity

>98% (HPLC)
Solubility

——
SMILES

O(C)C1=C(C2=C3N(N=C2)C=CC(=C3)C4=C5C(=NC=C4)NC=C5)C=C6C(=C1)CCNC6
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jacek Kwiatkowski, et al. Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors. J Med Chem. 2018 May 24;61(10):4386-4396. ?

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