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FLT3-IN-16

CAS No. 298207-49-5

FLT3-IN-16( —— )

Catalog No. M37680 CAS No. 298207-49-5

FLT3-IN-16 exhibits potent inhibitory activity against FLT3 tyrosine kinase with an IC 50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 53 In Stock
2MG 29 In Stock
5MG 48 In Stock
10MG 79 In Stock
25MG 181 In Stock
50MG 269 In Stock
100MG 381 In Stock
200MG 503 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    FLT3-IN-16
  • Note
    Research use only, not for human use.
  • Brief Description
    FLT3-IN-16 exhibits potent inhibitory activity against FLT3 tyrosine kinase with an IC 50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia .
  • Description
    FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia.
  • In Vitro
    FLT3-IN-16 (compound 9, 0-10 μM) exhibits anti-proliferative activities against MV4-11 cells with an IC50 value of 2.0 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    298207-49-5
  • Formula Weight
    301.36
  • Molecular Formula
    C15H15N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (82.96 mM; Ultrasonic (<80°C)
  • SMILES
    NC(=O)c1c(NC(=O)c2cccnc2)sc2CCCCc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Patch RJ, et, al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6.?
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