GX 201( —— )

Catalog No. M37645 CAS No. 1788071-27-1

GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	163	Get Quote
5MG	250	Get Quote
10MG	377	Get Quote
25MG	609	Get Quote
50MG	877	Get Quote
100MG	1188	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

GX 201
Note

Research use only, not for human use.
Brief Description

GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.
Description

GX-201 is a selective NaV1.7 inhibitor, with an IC50 of <3.2 nM for hNaV1.7.
In Vitro

——
In Vivo

Animal Model:Wild-Type Mice.Dosage:0.3, 1, 3 mg/kg.Administration:Orally, once.Result:Produced a dose-dependent inhibition of the nociceptive events.
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

Sodium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

1788071-27-1
Formula Weight

563
Molecular Formula

C25H27ClF4N2O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 62.5 mg/mL (111.01 mM; Ultrasonic )
SMILES

CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3cc(ccc3Cl)C(F)(F)F)CC2)cc1F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Girish Bankar, et al. Selective Na V 1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain. Cell Rep. 2018 Sep 18;24(12):3133-3145.?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks