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PY-60

CAS No. 2765218-56-0

PY-60( —— )

Catalog No. M37636 CAS No. 2765218-56-0

PY-60 can effectively activate YAP transcriptional activity against annexin A2 (ANXA2) (Kd value of 1.4 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	128	In Stock
5MG	117	In Stock
10MG	187	In Stock
25MG	376	In Stock
50MG	529	In Stock
100MG	731	In Stock
200MG	1004	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

PY-60
Note

Research use only, not for human use.
Brief Description

PY-60 can effectively activate YAP transcriptional activity against annexin A2 (ANXA2) (Kd value of 1.4 μM).
Description

PY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 μM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

YAP | Annexin A
Research Area

——
Indication

——

Chemical Information

CAS Number

2765218-56-0
Formula Weight

313.37
Molecular Formula

C16H15N3O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (319.11 mM; Ultrasonic )
SMILES

C(NCCCC1=NC=CS1)(=O)C=2C=C(ON2)C3=CC=CC=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Shalhout SZ, et al. YAP-dependent proliferation by a small molecule targeting annexin A2. Nat Chem Biol. 2021;17(7):767-775.?

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