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mTOR inhibitor 13
CAS No. 1144075-44-4
mTOR inhibitor 13( —— )
Catalog No. M37620 CAS No. 1144075-44-4
mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 299 | Get Quote |
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| 5MG | 455 | Get Quote |
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| 10MG | 620 | Get Quote |
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| 25MG | 911 | Get Quote |
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| 50MG | 1224 | Get Quote |
|
| 100MG | 1575 | Get Quote |
|
| 200MG | 2133 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamemTOR inhibitor 13
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NoteResearch use only, not for human use.
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Brief DescriptionmTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively.
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DescriptionmTOR inhibitor-13 (compound 9g), an aryl ureido compound, is a potent and selective mTOR inhibitor with an IC50 of 0.29 nM. mTOR inhibitor-13 also inhibits PI3K-α with an IC50 of 119 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorPI3K | mTOR
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Research Area——
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Indication——
Chemical Information
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CAS Number1144075-44-4
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Formula Weight458.54
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Molecular FormulaC24H22N6O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C(NC=1C=CC=NC1)=O)C2=CC=C(C3=NC(=C4C(=N3)C=CS4)N5CC6OC(C5)CC6)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jeroen C Verheijen, et al. Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K. Bioorg Med Chem Lett. 2010 Jan 1;20(1):375-9. ?
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