NR2E3 agonist 1( —— )

Catalog No. M37530 CAS No. 911211-69-3

NR2E3 agonist 1 is a small molecule photoreceptor-specific nuclear receptor (NR2E3) agonist with antitumor activity for the study of diseases caused by abnormalities in photoreceptor cell-specific receptors.

Purity : >98% (HPLC)

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HNMR

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Biological Information

Product Name

NR2E3 agonist 1
Note

Research use only, not for human use.
Brief Description

NR2E3 agonist 1 is a small molecule photoreceptor-specific nuclear receptor (NR2E3) agonist with antitumor activity for the study of diseases caused by abnormalities in photoreceptor cell-specific receptors.
Description

NR2E3 agonist 1 (Compound 11a) is a small molecule agonist of the photoreceptor-specific nuclear receptor (NR2E3) with an EC50 value of less than 200 nM. NR2E3 agonist 1 can be used in retinitis pigmentosa research.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

911211-69-3
Formula Weight

430.89
Molecular Formula

C24H19ClN4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(NC=1C=CC(=CC1)C2=NC3=CC(=CC=C3N2)NC(=O)C4CC4)C=5C=CC=CC5Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wolkenberg SE, et al. Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5001-4.?

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