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C 101248

CAS No. 361368-24-3

C 101248( —— )

Catalog No. M37356 CAS No. 361368-24-3

C 101248 is a selective and potent inhibitor targeting both mouse and human tandem pore domain halothane-inhibited K+ channel 1 (THIK-1, IC50= 50 nM), without affecting the K2P family members (TREK-1, TWIK-2) and Kv2.1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    C 101248
  • Note
    Research use only, not for human use.
  • Brief Description
    C 101248 is a selective and potent inhibitor targeting both mouse and human tandem pore domain halothane-inhibited K+ channel 1 (THIK-1, IC50= 50 nM), without affecting the K2P family members (TREK-1, TWIK-2) and Kv2.1.
  • Description
    KCNK13-IN-1 (example 71), a KCNK13 antagonist, is an anti-inflammatory agent, with an IC50 of <200 nM for IL-1 β.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    361368-24-3
  • Formula Weight
    292.3
  • Molecular Formula
    C15H12N6O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NC1=NON=C1C2=NC3=CC=CC=C3N2CC4=CC=NC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Roland BüRLI, et al. Novel compounds. Patent WO2022167819.
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