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NPAS3-IN-1

CAS No. 2207-44-5

NPAS3-IN-1( —— )

Catalog No. M37303 CAS No. 2207-44-5

NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, modulating NPAS3 transcription by targeting the interaction between NPAS3 and ARNT at the cellular level.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NPAS3-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, modulating NPAS3 transcription by targeting the interaction between NPAS3 and ARNT at the cellular level.
  • Description
    NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2207-44-5
  • Formula Weight
    295.36
  • Molecular Formula
    C10H5N3O2S3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (84.64 mM; Ultrasonic )
  • SMILES
    O=[N+]([O-])C1=CN=C(SC2=NC3=C(S2)C=CC=C3)S1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Li P, et al. Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT. Bioorg Chem. 2023 Oct;139:106676.?
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