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STAT6-IN-2

CAS No. 1355594-85-2

STAT6-IN-2( —— )

Catalog No. M37229 CAS No. 1355594-85-2

STAT6-IN-2 (Comp R-84) is a STAT6 inhibitor that effectively reduces the secretion of the chemokine eotaxin-3, which induces eosinophil infiltration. This compound is valuable for studying immune diseases .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 170 In Stock
10MG 282 In Stock
25MG 548 In Stock
50MG 877 In Stock
100MG 1377 In Stock
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Biological Information

  • Product Name
    STAT6-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    STAT6-IN-2 (Comp R-84) is a STAT6 inhibitor that effectively reduces the secretion of the chemokine eotaxin-3, which induces eosinophil infiltration. This compound is valuable for studying immune diseases .
  • Description
    STAT6-IN-2 (Comp R-84) is an inhibitor of STAT6. STAT6-IN-2 inhibits the secretion of chemokine eliciting eosinophil infiltration eotaxin-3. STAT6-IN-2 can be used for immune disease research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1355594-85-2
  • Formula Weight
    469.58
  • Molecular Formula
    C28H31N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (212.96 mM; Ultrasonic )
  • SMILES
    CN1C(C=2C=C(C(N[C@@H](C(C)C)C)=O)N=C(C(NCCC3=CC=CC=N3)=O)C2)=CC=4C1=CC=CC4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhou L, et.al. STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells. Bioorg Med Chem. 2012 Jan 15;20(2):750-8.?
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