PLpro/RBD-IN-1( —— )

Catalog No. M37210 CAS No. 1282451-83-5

PLpro/RBD-IN-1 is a dual inhibitor of SARS-CoV-2 PLpro and the spiny protein RBD, with anti-novel coronavirus activity, and is seen for the study of viral infections.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	562	In Stock
25MG	866	In Stock
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Biological Information

Product Name

PLpro/RBD-IN-1
Note

Research use only, not for human use.
Brief Description

PLpro/RBD-IN-1 is a dual inhibitor of SARS-CoV-2 PLpro and the spiny protein RBD, with anti-novel coronavirus activity, and is seen for the study of viral infections.
Description

PLpro/RBD-IN-1 (compound 5) is a dual SARS-CoV-2 PLpro and spike protein RBD inhibitor with IC50s of 7.197 μM and 8.673 μM, respectively.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

SARS-CoV
Research Area

——
Indication

——

Chemical Information

CAS Number

1282451-83-5
Formula Weight

238.24
Molecular Formula

C13H10N4O
Purity

>98% (HPLC)
Solubility

——
SMILES

N=1C=CC(=CC1)C2=NC(=NO2)C=3C=CC=CC3N
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Mohammed Salah Ayoup, et al. Repurposing 1,2,4-oxadiazoles as SARS-CoV-2 PLpro inhibitors and investigation of their possible viral entry blockade potential. Eur J Med Chem. 2023 Apr 5;252:115272.?

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