JNK-IN-13

CAS No. 345986-38-1

JNK-IN-13( —— )

Catalog No. M37058 CAS No. 345986-38-1

JNK-IN-13 is a selective and potent JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 31 In Stock
25MG 49 In Stock
50MG 79 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    JNK-IN-13
  • Note
    Research use only, not for human use.
  • Brief Description
    JNK-IN-13 is a selective and potent JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.
  • Description
    JNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    JNK
  • Recptor
    JNK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    345986-38-1
  • Formula Weight
    286.74
  • Molecular Formula
    C13H7ClN4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 31 mg/mL (108.11 mM )
  • SMILES
    Clc1nccc(n1)C(C#N)c1nc2ccccc2s1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Serge Halazy, et al. Benzazole derivatives and their use as JNK modulators. EP1110957A1.
molnova catalog
related products
  • Norharmane

    Norharmane is a natural β-carboline first isolated from plants of the Zygophyllaceae family.

  • AS601245

    AS601245, an anti-Inflammatory JNK inhibitor, and Clofibrate have a synergistic effect in inducing cell responses and in affecting the gene expression profile in CaCo-2 colon cancer cells .

  • Tanzisertib

    Tanzisertib (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.Tanzisertib (CC-930) inhibits the formation of phospho-cJun in human PBMC stimulated by phorbol-12-myristate-13-acetate and phytohemeagglutinin (IC50=1 μM)[1] and it blocks the JNK pathway that is activated by pro-fibrotic cytokines in systemic sclerosis.