RS5517
CAS No. 2227017-46-9
RS5517( —— )
Catalog No. M37024 CAS No. 2227017-46-9
RS5517 is a novel PDZ1 structural domain ligand for the study of colorectal cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 150 | In Stock |
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| 10MG | 221 | In Stock |
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| 25MG | 372 | In Stock |
|
| 50MG | 538 | In Stock |
|
| 100MG | 787 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2437 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRS5517
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NoteResearch use only, not for human use.
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Brief DescriptionRS5517 is a novel PDZ1 structural domain ligand for the study of colorectal cancer.
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DescriptionRS5517 is a specific PDZ1-domain antagonist of NHERF1 that prevented its ectopic nuclear entry. RS5517 can be used for the research of colorectal cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2227017-46-9
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Formula Weight390.86
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Molecular FormulaC23H19ClN2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1=CC=C(C=C1)CO)C=2NC=3C=CC(Cl)=CC3C2CC=4C=CC=CC4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Mast cell degranulat...
Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.
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3-Epiursolic acid
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the development of novel anticancer agents.
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PKC ζ pseudosubstrat...
Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide. Induces mast cell degranulation by a PKC ζ-independent pathway.
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