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Tubulin polymerization-IN-43
CAS No. 2773345-90-5
Tubulin polymerization-IN-43( —— )
Catalog No. M37016 CAS No. 2773345-90-5
Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 240 | Get Quote |
|
| 5MG | 330 | Get Quote |
|
| 10MG | 468 | Get Quote |
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| 25MG | 751 | Get Quote |
|
| 50MG | 994 | Get Quote |
|
| 100MG | 1332 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTubulin polymerization-IN-43
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NoteResearch use only, not for human use.
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Brief DescriptionTubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.
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DescriptionTubulin polymerization-IN-43 (compound 15h) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-43 disrupts cellular microtubule networks by targeting the Colchicine (HY-16569) site, and promots cell cycle arrest of leukemia cells at G2/M phase and cell apoptosis, as well as inhibiting angiogenesis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis | Microtubule Associated
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Research Area——
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Indication——
Chemical Information
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CAS Number2773345-90-5
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Formula Weight351.3
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Molecular FormulaC17H13F4N3O
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C)(C=1C2=C(N=C(C(F)(F)F)N1)C=CC(F)=C2)C3=CC=C(OC)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wu H, et, al. Discovery of novel N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as the inhibitors of tubulin polymerization in leukemia cells. Eur J Med Chem. 2023 Aug 5;256:115470.?
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