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LSD1-IN-27
CAS No. 2904571-94-2
LSD1-IN-27( —— )
Catalog No. M37006 CAS No. 2904571-94-2
LSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 359 | In Stock |
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| 10MG | 511 | In Stock |
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| 25MG | 848 | In Stock |
|
| 50MG | 1097 | In Stock |
|
| 100MG | 1507 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLSD1-IN-27
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NoteResearch use only, not for human use.
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Brief DescriptionLSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.
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DescriptionLSD1-IN-27 (Compound 5ac) is a LSD1 inhibitor (IC50: 13 nM). LSD1-IN-27 inhibits the stemness and migration of gastric cancer cells. LSD1-IN-27 also reduces the expression of PD-L1 in BGC-823 and MFC cells. LSD1-IN-27 can enhance T cell immune response in gastric cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorHistone Demethylase | PD-1/PD-L1
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Research Area——
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Indication——
Chemical Information
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CAS Number2904571-94-2
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Formula Weight355.48
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Molecular FormulaC24H25N3
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C=1C2=C(N=C3C1C=C(C)C=C3)C(C)=C(C)C=C2)C4=CC=C(N(C)C)C=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dai XJ, et al. Novel acridine-based LSD1 inhibitors enhance immune response in gastric cancer. Eur J Med Chem. 2023 Nov 5;259:115684.?
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