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KSK67
CAS No. 2566715-93-1
KSK67( —— )
Catalog No. M36971 CAS No. 2566715-93-1
KSK67 is a selective dual antagonist of sigma-2 and histamine H3 receptors with inhibitory effects on H3 receptors, sigma-1, and sigma-2 receptors, with Ki values of 3.2, 1531, and 101 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 65 | In Stock |
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| 10MG | 97 | In Stock |
|
| 25MG | 195 | In Stock |
|
| 50MG | 330 | In Stock |
|
| 100MG | 570 | In Stock |
|
| 200MG | 768 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKSK67
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NoteResearch use only, not for human use.
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Brief DescriptionKSK67 is a selective dual antagonist of sigma-2 and histamine H3 receptors with inhibitory effects on H3 receptors, sigma-1, and sigma-2 receptors, with Ki values of 3.2, 1531, and 101 nM, respectively.
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DescriptionKSK67 is a high-affinity dual sigma-2 and histamine H3 receptor antagonist, with Kis of 3.2, 1531, 101 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK67 can be used for research of nociceptive and neuropathic pain.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetSigma receptor
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RecptorSigma receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2566715-93-1
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Formula Weight365.47
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Molecular FormulaC22H27N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CC=C(OCCCN2CCN(C=3C=CN=CC3)CC2)C=C1)C4CC4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Szczepańska K, et al. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. J Med Chem. 2023 Jul 27;66(14):9658-9683.?
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