Cart
sales@molnova.com
hBChE-IN-2
CAS No. 2923366-36-1
hBChE-IN-2( —— )
Catalog No. M36924 CAS No. 2923366-36-1
hBChE-IN-2 is a butyrylcholinesterase (BChE) inhibitor and cannabinoid receptor 2 (CB2R) agonist with neuroprotective activity for the study of Alzheimer's disease-like neurological disorders.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 459 | In Stock |
|
| 10MG | 657 | In Stock |
|
| 25MG | 1026 | In Stock |
|
| 50MG | 1386 | In Stock |
|
| 100MG | 1832 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamehBChE-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionhBChE-IN-2 is a butyrylcholinesterase (BChE) inhibitor and cannabinoid receptor 2 (CB2R) agonist with neuroprotective activity for the study of Alzheimer's disease-like neurological disorders.
-
DescriptionhBChE-IN-2 (compound 15d) is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist. hBChE-IN-2 has neuroprotection activities.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetAChR
-
RecptorAChR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2923366-36-1
-
Formula Weight464.6
-
Molecular FormulaC27H36N4O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(OC1=CC=C(C=C1)CC2=NC=3C=C(C=CC3N2CCC(C)C)C(=O)N(CC)CC)N(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Philipp Spatz, et al. Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer's Disease Mouse Model. J Med Chem. 2023 May 11;66(9):6414-6435. ?
molnova catalog
related products
-
Nebracetam hydrochlo...
Nebracetam hydrochloride is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration.
-
VU0152100
VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).
-
Thiacloprid
Thiacloprid, a chloronicotinyl insecticide, acts as a selective agonist at insect nAChRs. The IC50 values are 2.7 and 860 nM for Drosophilan AChRs and M10 mouse fibroblast cells expressing α4β2 subunit-containing nAChRs, respectively.
