hBChE-IN-2( —— )

Catalog No. M36924 CAS No. 2923366-36-1

hBChE-IN-2 is a butyrylcholinesterase (BChE) inhibitor and cannabinoid receptor 2 (CB2R) agonist with neuroprotective activity for the study of Alzheimer's disease-like neurological disorders.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	657	In Stock
25MG	1026	In Stock
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Biological Information

Product Name

hBChE-IN-2
Note

Research use only, not for human use.
Brief Description

hBChE-IN-2 is a butyrylcholinesterase (BChE) inhibitor and cannabinoid receptor 2 (CB2R) agonist with neuroprotective activity for the study of Alzheimer's disease-like neurological disorders.
Description

hBChE-IN-2 (compound 15d) is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist. hBChE-IN-2 has neuroprotection activities.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

AChR
Recptor

AChR
Research Area

——
Indication

——

Chemical Information

CAS Number

2923366-36-1
Formula Weight

464.6
Molecular Formula

C27H36N4O3
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(OC1=CC=C(C=C1)CC2=NC=3C=C(C=CC3N2CCC(C)C)C(=O)N(CC)CC)N(C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Philipp Spatz, et al. Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer's Disease Mouse Model. J Med Chem. 2023 May 11;66(9):6414-6435. ?

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