Emicizumab( —— )

Catalog No. M36904 CAS No. 1610943-06-0

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Product Name

Emicizumab
Note

Research use only, not for human use.
Brief Description

Emicizumab(ACE 910) is a bispecific monoclonal antibody that bridges activated factor IX and activated factor X to mimic the function of activated factor VIII. Emicizumab is used for the prevention and treatment of hemophilia A.
Description

Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research.
In Vitro

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In Vivo

Animal Model:FVIII-deficient mice Dosage:1.5-10 mg/kg Administration:IV, 24 hours before tail-clip bleeding was performed Result:Significantly reduced blood loss in a tail-clip-bleeding model using FVIII-deficient mice.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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1. Ferrière S, et al. A hemophilia A mouse model for the in vivo assessment of emicizumab function. Blood. 2020 Aug 6;136(6):740-748.?

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