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Bexmarilimab
CAS No. 2259301-27-2
Bexmarilimab( —— )
Catalog No. M36875 CAS No. 2259301-27-2
Bexmarilimab (FP-1305) is a highly potent, humanized anti-CLEVER-1 IgG4 antibody with an IC50 value of 4.51 nM, promoting immune conversion of tumor-associated macrophage phenotype M2 to M1, and can be used to study cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 471 | In Stock |
|
| 10MG | 755 | In Stock |
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| 25MG | 1121 | In Stock |
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| 50MG | 1469 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBexmarilimab
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NoteResearch use only, not for human use.
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Brief DescriptionBexmarilimab (FP-1305) is a highly potent, humanized anti-CLEVER-1 IgG4 antibody with an IC50 value of 4.51 nM, promoting immune conversion of tumor-associated macrophage phenotype M2 to M1, and can be used to study cancer.
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DescriptionBexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4-antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2259301-27-2
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Formula Weight
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hollmén M, et, al. Nonclinical Characterization of Bexmarilimab, a Clever-1-Targeting Antibody for Supporting Immune Defense Against Cancers. Mol Cancer Ther. 2022 Jul 5;21(7):1207-1218.?
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