Cart
sales@molnova.com
Home - Products - Others - Other Targets - Letolizumab

Letolizumab

CAS No. 1450981-87-9

Letolizumab( —— )

Catalog No. M36807 CAS No. 1450981-87-9

Letolizumab (BMS-986004) is a dimeric antibody targeting CD40L for the expression of mutant IgG1 that lacks effector functions including Fc binding and complement binding.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 426 In Stock
10MG 679 In Stock
25MG 1026 In Stock
50MG 1358 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Letolizumab
  • Note
    Research use only, not for human use.
  • Brief Description
    Letolizumab (BMS-986004) is a dimeric antibody targeting CD40L for the expression of mutant IgG1 that lacks effector functions including Fc binding and complement binding.
  • Description
    Letolizumab (BMS-986004) is a monoclonal antibody targeting CD40L, which is produced to express mutant IgG1 lacking effector function, including Fc binding and complement fixation. Letolizumab reduces rejection, thromboembolism and prolongs the survival time.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Rhesus macaques after renal transplantation.Dosage:2, 10 and 20 mg/kg.Administration:Intravenous injection; once a week for 10 weeks.Result:Increased the survival time.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Immunology/Inflammation related
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1450981-87-9
  • Formula Weight
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Karnell JL, et al. Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond. Adv Drug Deliv Rev. 2019 Feb 15;141:92-103. ?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 8-Hydroxypinoresinol...

    8-Hydroxypinoresinol diglucoside is a natural product for research related to life sciences.

  • Chlorogenic Acid

    Chlorogenic acid(NSC-407296; 3-O-Caffeoylquinic acid) is one of the most abundant polyphenols in the human diet, has been reported to inhibit Y cell growth and a major anti-inflammatory constituent of lonicerae flos extract.

  • diethyl hexyl phtha...

    Bis(2-ethylhexyl) Phthalate plasticizer is used to impart softness and flexibility to PVC products. Bis(2-ethylhexyl) Phthalate has been implicated in obesity and insulin resistance. It inhibits prostaglandin synthesis and adversely affects the endocrine system.

Sign In Join Free