Oxelumab

CAS No. 1186098-83-8

Oxelumab( —— )

Catalog No. M36764 CAS No. 1186098-83-8

Oxelumab (R 4930) is a human monoclonal antibody targeting OX40L, and could be used to study asthma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 429 In Stock
10MG 677 In Stock
25MG 1026 In Stock
50MG 1358 In Stock
100MG 1832 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Oxelumab
  • Note
    Research use only, not for human use.
  • Brief Description
    Oxelumab (R 4930) is a human monoclonal antibody targeting OX40L, and could be used to study asthma.
  • Description
    Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma.
  • In Vitro
    Cell Proliferation Assay Cell Line:Natural Killer (NK) cell lines Concentration:10 μg/mL Incubation Time:3 days Result:Inhibited cell proliferation of NK cells.
  • In Vivo
    Animal Model:NSG mice with PBMCs from UC patients with simple clinical colitis activity index (SCCAI) Dosage:5 and 30 mg/kg Administration:Intraperitoneal injectionon; 5 and 30 mg/kg, once daily, on days 6 and 13 Result:Reversed the ethanol-induced colon dilated and the lost of distinct pattern of pellets. Decreased the level of IL-6 and increased the concentrations of glutamic acid. Reduced frequencies of splenic human effector memory T cells and switched B cells.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Interleukin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1186098-83-8
  • Formula Weight
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Youngblood BA, et al. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. Int Arch Allergy Immunol. 2019;180(2):91-102.?
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