Spesolimab( —— )

Catalog No. M36760 CAS No. 2097104-58-8

Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways.

Purity : >98% (HPLC)

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Biological Information

Product Name

Spesolimab
Note

Research use only, not for human use.
Brief Description

Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways.
Description

Spesolimab (BI 655130) is an anti-IL-36R antibody. IL-36 involves in immune system, as Spesolimab can be used for palmoplantar pustulosis (PPP) research. Spesolimab is associated with the reduction of biomarkers linked to innate, Th1/Th17, and neutrophilic pathways.
In Vitro

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In Vivo

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Synonyms

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Pathway

Apoptosis
Target

IL Receptor
Recptor

IL Receptor
Research Area

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Indication

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Chemical Information

CAS Number

2097104-58-8
Formula Weight
Molecular Formula

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Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Mrowietz U, et al. Spesolimab, an Anti-Interleukin-36 Receptor Antibody, in Patients with Palmoplantar Pustulosis: Results of a Phase IIa, Multicenter, Double-Blind, Randomized, Placebo-Controlled Pilot Study. Dermatol Ther (Heidelb). 2021 Apr;11(2):571-585.?

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