Volagidemab( —— )

Catalog No. M36755 CAS No. 1233956-13-2

Volagidemab, a monoclonal antibody (mAb) that antagonizes the glucagon receptor (GCGR), is utilized in researching Type 1 Diabetes (T1D) .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
2MG	445	Get Quote
5MG	687	Get Quote
10MG	937	Get Quote
25MG	1371	Get Quote
50MG	1812	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Volagidemab
Note

Research use only, not for human use.
Brief Description

Volagidemab, a monoclonal antibody (mAb) that antagonizes the glucagon receptor (GCGR), is utilized in researching Type 1 Diabetes (T1D) .
Description

Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb).Volagidemab can be used in the research of type 1 diabetes (T1D).
In Vitro

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In Vivo

Animal Model:Alloxan-induced diabetic mice Dosage:5 mg/kg Administration:Subcutaneous injection (s.c.)Result:Reduced phosphorylated CREB protein and PEPCK protein expression to nondiabetic levels.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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Chemical Information

CAS Number

1233956-13-2
Formula Weight
Molecular Formula

——
Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pettus J, et al. Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial. Nat Med. 2022 Oct;28(10):2092-2099. ?

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