Volagidemab( —— )

Catalog No. M36755 CAS No. 1233956-13-2

Volagidemab, a monoclonal antibody (mAb) that antagonizes the glucagon receptor (GCGR), is utilized in researching Type 1 Diabetes (T1D) .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Volagidemab
Note

Research use only, not for human use.
Brief Description

Volagidemab, a monoclonal antibody (mAb) that antagonizes the glucagon receptor (GCGR), is utilized in researching Type 1 Diabetes (T1D) .
Description

Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb).Volagidemab can be used in the research of type 1 diabetes (T1D).
In Vitro

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In Vivo

Animal Model:Alloxan-induced diabetic mice Dosage:5 mg/kg Administration:Subcutaneous injection (s.c.)Result:Reduced phosphorylated CREB protein and PEPCK protein expression to nondiabetic levels.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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Chemical Information

CAS Number

1233956-13-2
Formula Weight
Molecular Formula

——
Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pettus J, et al. Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial. Nat Med. 2022 Oct;28(10):2092-2099. ?

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