Tesidolumab

CAS No. 1531594-08-7

Tesidolumab( —— )

Catalog No. M36737 CAS No. 1531594-08-7

Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 471 In Stock
10MG 787 In Stock
25MG 1169 In Stock
50MG 1535 In Stock
100MG 2074 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Tesidolumab
  • Note
    Research use only, not for human use.
  • Brief Description
    Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody.
  • Description
    Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex.
  • In Vitro
    Tesidolumab (LFG316) possesses a half-life in humans of approximately 9 days.Tesidolumab (LFG316) binds to a distinct epitope to that of eculizumab and ravulizumab, distant to Arg 885.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Complement System
  • Recptor
    Complement System
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1531594-08-7
  • Formula Weight
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jun-Ichi Nishimura, et al. Tesidolumab (LFG316) for treatment of C5-variant patients with paroxysmal nocturnal hemoglobinuria. Haematologica. 2022 Jun 1;107(6):1483-1488.?
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