Cart
sales@molnova.com
I-152
CAS No. 311343-11-0
I-152( —— )
Catalog No. M36625 CAS No. 311343-11-0
I-152, a conjugate of N-acetyl-cysteine (NAC) and cysteamine (MEA), activates NRF2 and ATF4 signaling pathways and exhibits anti-proliferative properties .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 200 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameI-152
-
NoteResearch use only, not for human use.
-
Brief DescriptionI-152, a conjugate of N-acetyl-cysteine (NAC) and cysteamine (MEA), activates NRF2 and ATF4 signaling pathways and exhibits anti-proliferative properties .
-
DescriptionI-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties.
-
In VitroWestern Blot Analysis Cell Line:RAW 264.7 cells.Concentration:0.062, 0.125, 0.25, 1, 5 or 10 mM.Incubation Time:2 h or 24 h.Result:Reduced the expression of NRF2/β-ACTIN, increased the expression of GCLM.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number311343-11-0
-
Formula Weight264.36
-
Molecular FormulaC9H16N2O3S2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (378.27 mM; Ultrasonic )
-
SMILES[C@H](C(NCCSC(C)=O)=O)(NC(C)=O)CS
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Crinelli R, et al. Activation of NRF2 and ATF4 Signaling by the Pro-Glutathione Molecule I-152, a Co-Drug of N-Acetyl-Cysteine and Cysteamine. Antioxidants (Basel). 2021 Jan 26;10(2):175. ?
molnova catalog
related products
-
Ethylparaben
Ethylparaben is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative.
-
2-Pyrimidinamine, 4-...
2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)- is a marine derived natural products found in Aplidium meridianum.
-
Endotoxin Inhibitor
Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality.
