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JPD447

CAS No. 2883235-86-5

JPD447( —— )

Catalog No. M36587 CAS No. 2883235-86-5

JPD447 is a MAC-0547630 derivative that potentiates UppS inhibitors of β-lactam antibiotics with antimicrobial activity and can be used to study bacterial infections.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    JPD447
  • Note
    Research use only, not for human use.
  • Brief Description
    JPD447 is a MAC-0547630 derivative that potentiates UppS inhibitors of β-lactam antibiotics with antimicrobial activity and can be used to study bacterial infections.
  • Description
    JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2883235-86-5
  • Formula Weight
    338.42
  • Molecular Formula
    C20H23FN4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (295.49 mM; Ultrasonic (<80°C)
  • SMILES
    FC1=CC=C(C=C1)C=2C=NN3C2N=C(C=C3N4CCCCCC4)CC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Workman SD, et al. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. J Med Chem. 2021 Sep 23;64(18):13540-13550. ?
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