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β-D-Glucan

CAS No. 9041-22-9

β-D-Glucan( —— )

Catalog No. M36586 CAS No. 9041-22-9

β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    β-D-Glucan
  • Note
    Research use only, not for human use.
  • Brief Description
    β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis.
  • Description
    β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery. β-d-glucan is an enteric delivery vehicle for probiotics.
  • In Vitro
    β-D-glucan dissolved in DMSO but not water inhibits MCF-7 cell proliferation in a concentration-dependent manner as measured by BrdU incorporation with an IC50 of ～164μg/mL. β-D-glucan dissolved in DMSO inhibits tamoxifen/endocrine-resistant LCC9 and LY2 cell proliferation with IC50 values of 4.6 and 24.2 μg/mL, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    9041-22-9
  • Formula Weight
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?1M NaOH : 50 mg/mL (Ultrasonic; (NaOH ，pH≈11)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Su Y, et al. pH-sensitive PEG-coated hyper-branched β-d-glucan derivative as carrier for CpG oligodeoxynucleotide delivery. Carbohydr Polym. 2020;246:116621. ?
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