CKK-E12

CAS No. 1432494-65-9

CKK-E12( —— )

Catalog No. M36583 CAS No. 1432494-65-9

CKK-E12 is a selective ionizable lipid that often binds to other lipids to form carrier mRNA lipid nanoparticles.CKK-E12 is used in the study of RNA-related diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 274 In Stock
5MG 155 In Stock
10MG 250 In Stock
25MG 503 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CKK-E12
  • Note
    Research use only, not for human use.
  • Brief Description
    CKK-E12 is a selective ionizable lipid that often binds to other lipids to form carrier mRNA lipid nanoparticles.CKK-E12 is used in the study of RNA-related diseases.
  • Description
    CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1432494-65-9
  • Formula Weight
    993.62
  • Molecular Formula
    C60H120N4O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (50.32 mM; Ultrasonic )
  • SMILES
    O=C1NC(C(=O)NC1CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dong Y, Love KT, Dorkin JR, et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates [published correction appears in Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5753].?Proc Natl Acad Sci U S A. 2014;111(11):3955-3960. ?
molnova catalog
related products
  • Vulpinic Acid

    Vulpinic Acid is a lichen metabolite with anti-inflammatory, antibacteria, properties, plant growth inhibitor.

  • Compound 3A

    Compound 3A can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.

  • Asimadoline

    Asimadoline is a proprietary small molecule therapeutic, originally developed to treat peripheral pain such as arthritis.