LEM-14-1189 B( —— )

Catalog No. M36485 CAS No. 2987501-17-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

LEM-14-1189 B
Note

Research use only, not for human use.
Brief Description

Lem-14-1189, a LEM-14 derivative, is a potent NSD inhibitor of the nuclear receptor binding SET domain, and has inhibitory effects on NSD1, NSD2, and NSD3, with IC50 of 418 μM, 111 μM, and 60 μM, respectively.
Description

Lem-14-1189, a LEM-14 derivative, is a potent NSD inhibitor of the nuclear receptor binding SET domain, and has inhibitory effects on NSD1, NSD2, and NSD3, with IC50 of 418 μM, 111 μM, and 60 μM, respectively. LEM-14-1189 has potential anticancer activity and can be used to study multiple myeloma (MM) and diseases of the blood system.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Histone Methyltransferase
Research Area

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Indication

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CAS Number

2987501-17-5
Formula Weight

682.81
Molecular Formula

C35H34N6O5S2
Purity

>98% (HPLC)
Solubility

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SMILES

C1CCC2=C(C1)C3=C(S2)N=C(NC3=O)CN(CCCNC(=O)C4=CC5=CC=CC=C5C(=O)O4)CC6=NC7=C(C8=C(S7)CCCC8)C(=O)N6
Chemical Name

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